Relaxed phylogenies and dating with confidence Sexy teenage dating sites
Fortunately, intermediate models employing relaxed molecular clocks have been described.
These models open the gate to a new field of “relaxed phylogenetics.” Here we introduce a new approach to performing relaxed phylogenetic analysis.
An alternative way of considering this is that the autocorrelation is so strong that very little of the variation in rate can be attributed to inherited factors.
uri=info:doi/10.1371/0040088&representation=PDF Citation: Drummond AJ, Ho SYW, Phillips MJ, Rambaut A ( Relaxed Phylogenetics and Dating with Confidence Alexei J. Fortunately, intermediate models employing relaxed molecular clocks have been described.
This development has been characterized by increases, both in the complexity of the models used to describe molecular sequence evolution, and in the sophistication of the methods for analyzing these new models.
Nevertheless, a well-known problem that has persistently troubled phylogenetic inference is that of substitution rate variation among lineages.
We describe how it can be used to estimate phylogenies and divergence times in the face of uncertainty in evolutionary rates and calibration times.
Our approach also provides a means for measuring the clocklikeness of datasets and comparing this measure between different genes and phylogenies.