Consolidating tasks

The standard model of synaptic consolidation suggests that alterations of synaptic protein synthesis and changes in membrane potential are achieved through activating intracellular transduction cascades.These molecular cascades trigger transcription factors that lead to changes in gene expression.

consolidating tasks-44

Protein synthesis plays an important role in the formation of new memories.After Molaison underwent a bilateral medial temporal lobe resection to alleviate epileptic symptoms the patient began to suffer from memory impairments.Molaison lost the ability to encode and consolidate newly learned information leading researchers to conclude the medial temporal lobe (MTL) was an important structure involved in this process.Synaptic consolidation is achieved faster than systems consolidation, within only minutes to hours of learning in goldfish.LTP, one of the best understood forms of synaptic plasticity, is thought to be a possible underlying process in synaptic consolidation.

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